Association of Higher Circulating Insulin Antibody with Increased Mean Amplitude Glycemic Excursion in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional, Retrospective Case-Control Study

Table 2

Glycemic variability among different IA titer groups.

	C	L	H	value/chi-square	value
Ln(MAGE) (mmol/l)		^a	^ab	12.610	<0.001
Ln(SDBG) (mmol/l)		^a	^a	6.984	0.001
LAGE (mmol/l)		^a	^a	9.928	<0.001
MBG (mmol/l)				0.170	0.844
(mmol/lmin)	0.00 (0.00, 98.25)	7.55 (0.00, 283.48)	173.79 (0.00, 565.20)^ab	10.492^c	0.005
PT1 (%)	0.00 (0.00, 10.07)	1.39 (0.00, 13.89)	9.10 (0.00, 22.31)^ab	8.100^c	0.017
(mmol/lmin)	0.00 (0.00, 0.00)	0.00 (0.00, 2.80)	0.00 (0.00, 17.92)^a	6.088^c	0.048
PT2 (%)	0.00 (0.00, 0.00)	0.00 (0.00, 1.31)	0.00 (0.00, 2.53)^a	5.391^c	0.048

Ln: base logarithm; MAGE: the 24 h mean amplitude of glycemic excursion; SDBG: the standard deviation of 24 h blood glucose; LAGE: the large amplitude of glycemic excursion; MBG: the 24 h mean blood glucose concentration; : the incremental area under the curve of plasma ; : the incremental area under the curve of plasma ; PT1: the percentage of the time spent on glucose concentrations above 13.9 mmol/l; PT2: the percentage of the time spent on glucose concentrations below 3.9 mmol/l. ^aCompared with the C group (); ^bcompared with the L group (); ^cnonparametric test. Data were presented as or median (25th, 75th percentile).