Research Article
Polymorphisms in NLRP1 Gene Are Associated with Type 1 Diabetes
Table 3
Frequencies of the genotype and allele of NLRP1 polymorphisms between cases and controls in the Chinese Han population.
| | SNP | Cases () (%) | Controls () (%) | OR (95% CI) | | () |
| | rs11651270 | | | | | | | Genotype | | | | | | | CC | 23 (4.51) | 30 (5.65) | 0.677 (0.385-1.191) | 0.174 | 0.348 | | CT | 145 (28.43) | 199 (37.48) | 0.643 (0.494-0.838) | 0.001 | 0.002 | | TT | 342 (67.06) | 302 (56.87) | — | — | — | | Allele | | | | | | | C | 191 (18.73) | 259 (24.39) | 0.714 (0.579-0.882) | 0.002 | 0.004 | | T | 829 (81.27) | 803 (75.61) | — | — | — | | rs2670660 | | | | | | | Genotype | | | | | | | GG | 14 (2.75) | 16 (3.01) | 0.823 (0.396-1.712) | 0.602 | — | | GA | 123 (24.12) | 164 (30.89) | 0.706 (0.536-0.930) | 0.013 | 0.026 | | AA | 373 (73.14) | 351 (66.10) | — | — | — | | Allele | | | | | | | G | 151 (14.80) | 196 (18.46) | 0.768 (0.609-0.968) | 0.025 | 0.050 | | A | 869 (85.20) | 866 (81.54) | — | — | — |
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SNP: single-nucleotide polymorphisms; OR: odds ratio; 95% CI: 95% confidence intervals; : value after correction for multiple comparisons. |
