Characterization of Novel Nonobese Type 2 Diabetes Rat Model with Enlarged Kidneys

Figure 2

Blood glucose levels after glucose loading in normal (square) and affected (triangle) males aged 15 ((a), normal , affected ) and 30 ((b), normal , affected ) weeks. (c) Areas under the curve (AUC) of blood glucose after glucose loading at the ages of 15 and 30 weeks. Open and closed bars represent normal and affected males, respectively. Plasma insulin levels after glucose loading in normal (square) and affected (triangle) males aged 15 ((d), normal , affected ) and 30 ((e), normal , affected ) weeks (e). (f) Insulin tolerance test at the age of 22 weeks. Affected rats were classified into three groups (triangle, ; circle, ; rhombus, ). Normal rats are depicted by open squares. , , and : normal vs. affected. : vs. 0 min.

(a)

(b)

(c)

(d)

(e)

(f)