Effects of Highly Absorbable Curcumin in Patients with Impaired Glucose Tolerance and Non-Insulin-Dependent Diabetes Mellitus

Table 3

Change of each parameter in patients treated with Theracurmin®.

Theracurmin®	0M (0 month)	3M	6M	value for trend test	value
					0M vs. 3M	0M vs. 6M	3M vs. 6M
BMI (kg/m^2)				0.992	0.307	0.518	0.118
SBP (mmHg)				0.936	0.637	0.744	0.906
DBP (mmHg)				0.746	0.704	0.875	0.801
HbA1c (%)	6.1 [6.0, 6.3]	6.2 [5.9, 6.7]	6.1 [5.9, 6.8]	0.933	0.179	0.552	0.719
BS (mg/dL)	109.5 [100.0, 145.8]	108.0 [99.3, 135.0]	99.0 [91.5, 122.8]	0.130	0.861	0.079	0.124
TG (mg/dL)	144.0 [86.0, 177.0]	147.0 [88.0, 219.0]	120.0 [87.0, 170.0]	0.669	0.245	0.532	0.015
LDL-C (mg/dL)				0.992	0.355	0.745	0.719
HDL-C (mg/dL)				0.546	0.509	0.266	0.279
UA (mg/dL)				0.684	0.797	0.438	0.833
γ-GTP (IU/L)	32.0 [21.0, 57.0]	33.0 [23.0, 57.0]	33.0 [21.0, 45.0]	0.917	0.239	0.432	0.007
Cre (mg/dL)	0.8 [0.6, 0.9]	0.8 [0.7, 0.9]	0.8 [0.7, 0.9]	0.677	0.330	0.161	0.551
SAA-LDL (μg/mL)	5.0 [4.0, 7.0]	6.0 [5.0, 9.3]	5.5 [4.0, 8.8]	0.935	0.223	0.837	0.858
AT-LDL (μg/mL)	1.1 [1.0, 1.3]	1.1 [1.0, 1.4]	1.1 [1.0, 1.3]	0.962	0.720	0.722	0.796
Adiponectin (μg/mL)				0.837	0.800	0.383	0.535
Leptin (ng/mL)	4.7 [2.1, 15.4]	3.8 [2.0, 14.6]	3.2 [2.3, 11.0]	0.588	0.695	0.084	0.075
hs-CRP (mg/dL)	0.6 [0.2, 1.1]	0.5 [0.3, 1.1]	0.5 [0.2, 1.2]	0.797	0.861	0.861	0.917
CCr (mL/min/1.73m^2)	72.4 [66.7, 95.0]	72.4 [58.6, 90.5]	71.6 [61.3, 90.8]	0.723	0.460	0.074	0.650

BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1c: hemoglobin A1c; BS: blood sugar; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; UA: uric acid; γ-GTP: γ-glutamyl transpeptidase; Cre: creatinine; SAA-LDL: serum amyloid A-LDL; AT-LDL: a1-antitrypsin-LDL; hs-CRP: high-sensitivity C-reactive protein; CCr: creatinine clearance.