(i) The prevalence of MS increased with OSA severity (ii) Obesity and OSA led to metabolic abnormalities with different patterns between the two sexes (iii) Metabolic score increased with the HOMA index
113 OSA patients, 45 controls; 82% men; only nonobese subjects included; no difference in BMI among groups
SDB: ; PSG
(i) Patients with OSA had significantly higher systolic blood pressure and triglyceride levels (ii) Dyslipidaemia, hypertension, and at least two of the NCEP criteria were significantly more frequent in the OSA group (iii) AHI was independently associated with increased triglycerides and insulin resistance (assessed with HOMA) in linear regression
42 OSA patients, 52 controls matched for age, BMI, and visceral fat accumulation; 100% men; only nonobese subjects included
SDB: ; PSG
(i) No significant differences in serum levels of triglycerides, HDL, and diastolic BP (ii) Prevalence of hyperglycaemia, dyslipidaemia, and hypertension was significantly higher in the OSA group (iii) Patients with OSA had more often at least two of the criteria hypertension, hyperglycaemia, and dyslipidaemia, independent of visceral fat obesity
(i) MS was more often present in patients with OSA (ii) Prevalence of hypertension was significantly higher in the OSA group (iii) No significant differences in hyperglycaemia and dyslipidaemia (iv) Prevalence of MS increased with severity of OSA
(i) The prevalence of MS was higher in the OSA group (ii) Logistic regression adjusted for age, BMI, and smoking showed an independent association of OSA and MS (iii) OSA was independently associated with the levels of triglycerides and glucose as well as the Epworth score values, whereas insulin resistance (assessed with HOMA) was not significant
(i) MS was significantly more frequent in patients with OSA (ii) The risk of MS was associated with the severity of OSA (iii) Hypertension, dyslipidaemia, and visceral obesity were more common in patients with OSA
(i) Patients with OSA had a greater waist circumference and higher systolic and diastolic blood pressure, were more insulin-resistant (assessed with HOMA), and had lower HDL and a higher prevalence of MS (ii) Patients with OSA were 9.1 times more likely to have MS
DM2: diabetes mellitus type 2; AHI: apnea-hypopnea index; PSG: polysomnography; OSA: obstructive sleep apnea; MS: metabolic syndrome; BP: blood pressure; BMI: body mass index; IDF: International Diabetes Federation; HDL: high-density lipoprotein; HOMA: Homeostasis Model Assessment; CPAP: continuous positive airway pressure.
We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at firstname.lastname@example.org to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.