Melatonin Affects Mitochondrial Fission/Fusion Dynamics in the Diabetic Retina

Figure 6

Melatonin treatments appear to prevent the development of microvascular complications. (a) Fluorescein angiography was used to visualize the intraocular vasculature in mice. AngioTool was used to determine the (b) percentage of vascular area to the retinal area and (c) the average vessel length. “AU” is the arbitrary unit used in the AngioTool software. The vascular area (percentage) and the average vessel length in STZ+MEL mice are significantly less than those in the STZ mice (). (d) Venous beading (rectangle) was observed in STZ mice. .

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