Vascular Events and Carotid Atherosclerosis: A 5-Year Prospective Cohort Study in Patients with Type 2 Diabetes and a Contemporary Cardiovascular Prevention Treatment

Table 2

Factors associated with new cardiovascular events in patients without prior cardiovascular events.

	Univariate model		Multivariate model
	HR (95% CI)	value	HR (95% CI)	value
Carotid atherosclerosis	1.43 (0.78–2.63)	0.247	1.05 (0.50–2.53)	0.735
Age	1.77 (1.34–2.35)	<0.001	1.67 (1.21–2.29)	0.002
Current smokers	0.69 (0.32–1.47)	0.335	1.13 (0.55–2.53)	0.773
Nephropathy^a	2.04 (1.16–3.58)	0.013	1.40 (0.77–2.53)	0.264
Antiplatelet treatment	1.73 (0.98–3.04)	0.058	1.38 (0.72–2.62)	0.331
	2.35 (1.33–4.15)	0.003	1.60 (0.87–2.95)	0.130

CI: confidence interval; HR: hazard ratio. ^aDefined by the presence of at least one of the following:  mL/min/1.73m², positive microalbuminuria, or positive proteinuria.