Association Study between BGLAP Gene HindIII Polymorphism and Type 2 Diabetes Mellitus Development in Ukrainian Population

Table 4

Association analysis between BGLAP HindIII and T2DM development.

Model		ORc (95% CI)		ORa (95% CI)
Dominant	0.155	0.746 (0.498-1.117)	0.169	0.745 (0.489-1.134)	0.676
Recessive	0.254	1.569 (0.723-3.406)	0.134	1.861 (0.826-4.191)	0.536
Overdominant	0.04	0.638 (0.415-0.979)	0.03	0.608 (0.389-0.952)	0.12
Additive^a	0.058	0.656 (0.425-1.015)	0.05	0.635 (0.403-1.0)	0.2
	0.437	1.366 (0.622-3.001)	0.26	1.606 (0.704-3.663)	1

: crude value; OR_c: crude odds ratio; : value after adjustment for age, sex, BMI, smoking, and arterial hypertension presence; OR_a: adjusted odds ratio; : value after Bonferroni correction. ^aUpper row describes the comparison between CT and TT genotypes and lower row between CC and TT genotypes.