Association Study between BGLAP Gene HindIII Polymorphism and Type 2 Diabetes Mellitus Development in Ukrainian Population

Table 5

Association analysis between BGLAP HindIII and T2DM development among obese and nonobese individuals.

Regression model^1			ORc (95% CI)			ORa (95% CI)
Dominant		0.011	0.387 (0.186-0.806)	0.029	0.018	0.399 (0.187-0.852)	0.046	0.072	0.184
		0.889	1.036 (0.634-1.693)		0.969	1.01 (0.609-1.675)		1
Recessive		0.221	4.179 (0.424-41.224)	0.419	0.193	4.868 (0.449-52.757)	0.402	0.772	1
		0.338	1.525 (0.643-3.616)		0.277	1.641 (0.672-4.01)		1
Overdominant		0.003	0.305 (0.141-0.661)	0.023	0.004	0.308 (0.138-0.687)	0.038	0.016	0.152
		0.692	0.9 (0.534-1.516)		0.575	0.858 (0.501-1.467)		1
Additive	CT vs. TT	0.004	0.318 (0.146-0.693)	0.024	0.006	0.319 (0.142-0.717)	0.037	0.024	0.148
		0.828	0.943 (0.553-1.605)		0.722	0.905 (0.522-1.568)		1
	CC vs. TT	0.37	2.864 (0.286-28.629)	0.605	0.293	3.581 (0.332-38.672)	0.527	1	1
		0.372	1.495 (0.619-3.61)		0.331	1.574 (0.631-3.928)		1

¹Upper row represents the results for individuals with and lower row for those with . : crude value; : crude value for interactive term; : value adjusted for age, sex, smoking, and arterial hypertension presence; : value adjusted for age, sex, smoking, and arterial hypertension presence for interaction term; : value adjusted for Bonferroni correction; : value adjusted for Bonferroni correction for interaction term.