Association Study between BGLAP Gene HindIII Polymorphism and Type 2 Diabetes Mellitus Development in Ukrainian Population
Table 6
Association analysis between BGLAP HindIII and T2DM development among males and females.
Regression model1
ORc (95% CI)
ORa (95% CI)
Dominant
0.406
0.794 (0.461-1.368)
0.705
0.511
0.829 (0.474-1.449)
0.594
1
1
0.216
0.678 (0.366-1.254)
0.198
0.658 (0.348-1.245)
0.792
Recessive
0.734
1.208 (0.406-3.596)
0.509
0.491
1.776 (0.336-9.405)
0.499
1
1
0.227
2.079 (0.634-6.822)
0.128
2.63 (0.756-9.147)
0.512
Overdominant
0.304
0.741 (0.419-1.312)
0.428
0.313
0.739 (0.411-1.33)
0.338
1
1
0.053
0.521 (0.269-1.008)
0.033
0.476 (0.241-0.941)
0.132
Additive
CT vs. TT
0.324
0.747 (0.419-1.333)
0.495
0.365
0.759 (0.418-1.379)
0.387
1
1
0.08
0.549 (0.281-1.073)
0.055
0.506 (0.252-1.014)
0.22
CC vs. TT
0.871
1.096 (0.363-3.314)
0.596
0.556
1.409 (0.45-4.412)
0.555
1
1
0.385
1.708 (0.511-5.711)
0.187
2.351 (0.66-8.377)
0.748
1Upper row represents the results for males and lower row for females. : crude value; : crude value for interactive term; : value adjusted for age, sex, smoking and arterial hypertension; : value adjusted for age, sex, smoking and arterial hypertension for interaction term; : value adjusted for Bonferroni correction; : value adjusted for Bonferroni correction for interaction term.
