Research Article
Glucose-Regulated Protein 78 in the Aqueous Humor of Patients with Diabetic Macular Edema
Table 3
Results of logistic regression, effect on responsiveness to intravitreal bevacizumab treatments.
| | Category | (%) | Univariate | Multivariate | | OR (95% CI) | | OR (95% CI) | |
| | Sex | Female | 38 (57.58%) | Reference | | | | | Male | 28 (42.42%) | 0.61 (0.21, 1.72) | 0.360 | | |
| | Age (years) | <60 | 30 (45.45%) | Reference | | | | | ≥60 | 36 (54.55%) | 0.84 (0.33, 1.27) | 0.558 | | |
| | HbA1c | ≤7 | 18 (%) | Reference | | | | | >7 | 48 (%) | 1.56 (0.50, 5.52) | 0.462 | | |
| | DMR stage | NPDR | 17 (27.27%) | Reference | | | | | PDR | 49 (72.73%) | 0.69 (0.22, 2.22) | 0.526 | | |
| | EZ disruption | (-) | 42 (63.64%) | Reference | | | | | (+) | 24 (36.36%) | 0.67 (0.22, 1.93) | 0.465 | | |
| | Number of HF | <8 | 29 (43.94%) | Reference | | Reference | | | ≥8 | 37 (56.06%) | 0.34 (0.12, 0.96) | 0.046 | 0.34 (0.12, 0.96) | 0.046 |
| | GRP78 (ng/mL) | >4.051 | 33 (50.00%) | Reference | | | | | <4.051 | 33 (50.00%) | 0.88 (0.31, 2.42) | 0.796 | | |
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OR: odds ratio; CI: confidence interval; HbA1c: glycated hemoglobin; DMR: DM retinopathy; EZ: ellipsoid zone; HF: hyperreflective foci; GRP78: glucose-regulated protein of 78 kDa.
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