Journal of Diabetes Research / 2020 / Article / Tab 3 / Clinical Study
Modifiable Variables Are Major Risk Factors for Posttransplant Diabetes Mellitus in a Time-Dependent Manner in Kidney Transplant: An Observational Cohort Study Table 3 Modifiable and nonmodifiable risk factors for developing PTDM including transplant-related variables.
Transplant-related variables PTDM (+) ( ) PTDM (-) ( ) OR 95% CI Inferior Upper Acute rejection (%, ) 45.9% (28) 30.8% (120) 0.02 0.53 0.30 0.91 Cumulative steroid dose (mg/kg) 0.14 1.00 0.99 1.01 Tacrolimus (%, ) 85.2% (52) 85% (331) 0.97 0.99 0.46 2.11 Mycophenolate of sodium (%, ) 44.2% (27) 54.7% (213) 0.13 1.52 0.88 2.62 Cyclosporine (%, ) 6.5% (4) 9.2% (36) 0.49 1.45 0.50 4.24 Azathioprine (%, ) 49.2% (30) 39.8% (155) 0.17 0.68 0.40 1.18 Sirolimus (%, ) 3.2% (2) 3.3% (13) 0.98 1.02 0.22 4.63 Everolimus (%, ) 9.8% (6) 6.4% (25) 0.33 0.63 0.25 1.60 CMV infection (%, ) 36% (22) 34.7% (135) 0.84 0.94 0.54 1.65 Transient hyperglycaemia (%, n) 86.8% (53) 18.5% (72) 0.0001 0.03 0.02 0.07 Delayed graft function (%, ) 31.1% (19) 34.2% (133) 0.64 1.15 0.64 2.05 Hypertension (%, ) 86.9% (53) 79.7% (310) 0.19 0.59 0.27 1.30 Calcium channel blockers (%, ) 70.5% (43) 53.5% (208) 0.014 0.48 0.27 0.86 β -Blockers (%, )54% (33) 41.9% (163) 0.07 0.61 0.36 1.05 at 6 months42.6% (26) 32.9% (128) 0.14 0.66 0.38 1.14 at 1 year55.7% (34) 38% (148) 0.01 0.49 0.28 0.84 at 2 years41% (25) 32.4% (126) 0.19 0.69 0.40 1.12 at 3 years52.4% (32) 25.7% (100) 0.0001 0.31 0.18 0.54 FK trough level at 1 month 0.004 1.11 1.03 1.19 FK trough level at 3 months 0.016 1.11 1.02 1.20 FK trough level at 6 months 0.009 1.12 1.03 1.22 FK trough level at 1 year 0.13 1.08 0.979 1.18 FK trough level at 2 years 0.18 1.06 0.972 1.16 FK trough level at 3 years 0.15 1.08 0.973 1.19