Maternally Inherited Diabetes Mellitus Associated with a Novel m.15897G>A Mutation in Mitochondrial tRNA^Thr Gene

Figure 10

Ratio of geometric mean intensity. Measurement of mitoROS. The levels of ROS generation by mitochondria in living cells from mutant and control cybrid cell lines were determined using the mitochondrial superoxide indicator MitoSOX Red. The average of the determinations for each cybrid cell line is shown. The error bars indicate two standard errors of the means. indicates the significance, according to the -test, of the differences between mutant and control cell lines.