Research Article

Maternally Inherited Diabetes Mellitus Associated with a Novel m.15897G>A Mutation in Mitochondrial tRNAThr Gene

Figure 7

Respiratory complex activities. The activities of respiratory complexes were investigated by enzymatic assay on complexes I, II, III, and IV in isolated mitochondria from lymphoblastoid cell lines derived from the mutant and control cybrid cell lines. Activities of complexes I, II, III, and IV were normalized by citrate synthase activity. and indicate the significance, according to the -test, of the differences between mutant and control cybrid cell lines.