The Effect of Diacerein on Type 2 Diabetic Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis

Table 3

Difference of complications between the diacerein group and control group.

Complications	Number of studies	Sample size of diacerein group	Sample size of control group	Risk ratio (95% CI)	value	Heterogeneity (, )
Gastrointestinal symptoms	4	104	103	1.39 (1.08~1.77)	0.009	0%, 0.85
Headache	2	63	61	1.25 (0.52~3.01)	0.61	0%, 0.86
Dizziness	1	43	41	1.43 (0.25~8.13)	0.69	Not available
Others	1	35	36	11.31 (0.65~197.11)	0.10	Not available

Gastrointestinal symptoms include diarrhea, nausea, vomiting, and abdominal pain. The categories of complications were not specified in the original article.