Research Article
Reduction in Serum High-Sensitivity C-Reactive Protein Favors Kidney Outcomes in Patients with Impaired Fasting Glucose or Diabetes
Table 1
Baseline characteristics of patients and divided by reduction in hs-CRP levels.
| | Characteristics | Total () | No reduction in hs-CRP levels () | Reduction in hs-CRP levels () | |
| | Age (year) | | | | <0.001 | | Male | 3013 (76.8) | 1702 (73.4) | 1311 (81.7) | <0.001 | | SBP (mmHg) | | | | <0.001 | | BMI (kg/m2) | | | | <0.001 | | Waist circumference (cm) | | | | <0.001 | | FBG (mmol/L) | 6.3 (5.9, 7.6) | 6.4 (5.9, 7.8) | 6.2 (5.8, 7.4) | <0.001 | | TC (mmol/L) | 5.1 (4.5, 5.8) | 5.1 (4.5, 5.9) | 5.1 (4.4, 5.7) | 0.10 | | TG (mmol/L) | 1.6 (1.1, 2.5) | 1.7 (1.2, 2.6) | 1.5 (1.0, 2.3) | <0.001 | | LDL-C (mmol/L) | 2.3 (1.4, 3.0) | 2.1 (0.7, 2.9) | 2.5 (2.0, 3.0) | <0.001 | | HDL-C (mmol/L) | 1.5 (1.3, 1.8) | 1.5 (1.3, 1.8) | 1.5 (1.3, 1.7) | <0.001 | | Uric acid (μmol/L) | | | | <0.001 | | eGFR (mL/min/1.73m2) | | | | <0.001 | | Baseline hs-CRP (mg/L) | 6.0 (4.0, 9.2) | 6.63 (4.4, 9.65) | 5.0 (3.7, 8.3) | <0.001 | | Proteinuria ( (%)) | 681 (18.1) | 425 (18.8) | 256 (17.3) | <0.001 | | Cigarette use ( (%)) | 1139 (31.4) | 557 (26.9) | 582 (37.2) | <0.001 | | Drinker ( (%)) | 1251 (34.5) | 588 (28.5) | 663 (42.5) | <0.001 | | Physical exercise ( (%)) | 615 (17.1) | 330 (16.1) | 285 (18.3) | 0.09 | | Hypertension ( (%)) | 2295 (58.5) | 1472 (63.5) | 823 (51.3) | <0.001 | | Diabetes ( (%)) | 1465 (37.3) | 915 (39.4) | 550 (34.3) | <0.001 | | Hypotensive drugs ( (%)) | 692 (34.2) | 412 (32.6) | 280 (36.8) | 0.052 |
|
|
Note: SBP = systolic blood pressure; BMI = body mass index; FBG = fasting blood glucose; TC = total cholesterol; TG = triglyceride; LDL-C = low-density lipoprotein cholesterol; HDL-C = high-density lipoprotein cholesterol; eGFR = estimated glomerular filtration rate.
|
