Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice

Table 5

Changes in ROS, SOD, CAT, MDA, and GSH-PX in kidney homogenates after different treatments ().

	Nor	Con	Pyr	Pyr-ORS
ROS (IU/mg protein)
Week 0
Week 8			^#	^#
SOD (U/mg protein)
Week 0	—	—	—	—
Week 8			^##	^#
CAT (U/mg protein)
Week 0	—	—	—	—
Week 8			^#	^##
MDA (μmol/mg protein)
Week 0
Week 8				^#
GSH-PX (μg/g protein)
Week 0	—	—	—	—
Week 8			^##	^#

Nor (normal), C57BLKS/J nontreated mice; Con (control), C57BLKS/J diabetic db/db nontreated mice; Pyr, db/db mice drunk distilled water containing 1% pyruvate; Pyr-ORS, db/db mice drunk pyruvate-enriched ORS to replace distilled water, containing 0.35% pyruvate; ROS: radical oxygen species; SOD: superoxide dismutase; CAT: catalase; MDA: malondialdehyde. and vs. Nor; ^# and ^## vs. Con. Values were at week 0 and at week 8, respectively.