Assessing the Relationship between Gestational Glycemic Control and Risk of Preterm Birth in Women with Type 1 Diabetes: A Joint Modeling Approach

Table 2

Parameter estimates and model fit statistics from the joint model and the time-dependent Cox model.

	Time-dependent Cox model			Joint model
				LSM	ESM
	EST (CI)	OR (CI)	M-Val	EST (CI)	OR (CI)	M-Val
Mother’s age at LMP	1.02 (0.95, 1.10)			1.29 (1.10, 1.72)
Age at diabetes onset	0.97 (0.92, 1.03)			0.84 (0.62, 0.98)
Presence of nephropathy		2.21 (1.01, 3.32)			2.29 (1.05, 4.48)
Association						-0.01
DIC			19,932			19,895
-2Log-likelihood			18,464			19,434

; CI refers to confidence and credible interval for the time-dependent Cox model and the joint model, respectively (see Methods); LSM: longitudinal submodel; ESM: event submodel; EST: estimate; OR: odds ratio, M-Val: model value.