3<i>β</i>-Hydroxysteroid-<i>Δ</i>24 Reductase (DHCR24) Protects Pancreatic <i>β</i> Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Scavenging Excessive Intracellular Reactive Oxygen Species

<div>MIN6 apoptosis induced by both cholesterol and H<sub>2</sub>O<sub>2</sub> is inhibited by overexpression of DHCR24. MIN6 cells were exposed to cholesterol (250× dilution) and H<sub>2</sub>O<sub>2</sub> (1 mM) 48 h postadenovirus infection. 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Journal of Diabetes Research

fig5

Figure 5

Figure 5: 3<i>β</i>-Hydroxysteroid-<i>Δ</i>24 Reductase (DHCR24) Protects Pancreatic <i>β</i> Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Scavenging Excessive Intracellular Reactive Oxygen Species 

Figure 5 | 3β-Hydroxysteroid-Δ24 Reductase (DHCR24) Protects Pancreatic β Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Scavenging Excessive Intracellular Reactive Oxygen Species 