Research Article

Poor Control of Plasma Triglycerides Is Associated with Early Decline of Estimated Glomerular Filtration Rates in New-Onset Type 2 Diabetes in China: Results from a 3-Year Follow-Up Study

Table 4

The associations of baseline and follow-up metabolic abnormalities with the most reduced eGFR.

Model 1Model 2
VariablesOR (95% CI) valueOR (95% CI) value

Baseline analysis
Age (per year)1.007 (0.977 to 1.038)0.6471.007 (0.976 to 1.039)0.670
Sex (female)1.380 (0.797 to 2.388)0.2501.322 (0.734 to 2.380)0.353
Overweight/obesity1.021 (0.579 to 1.799)0.9430.969 (0.537 to 1.747)0.917
Hypertension0.864 (0.518 to 1.443)0.5770.837 (0.494 to 1.418)0.508
Poor glycemic control1.369 (0.711 to 2.636)0.3471.321 (0.673 to 2.593)0.419
High TG1.420 (0.864 to 2.334)0.1661.413 (0.833 to 2.398)0.200
Low HDL-C1.277 (0.715 to 2.282)0.4090.992 (0.520 to 1.893)0.981
Out of target for LDL-C0.803 (0.401 to 1.607)0.5350.718 (0.351 to 1.469)0.364
Follow-up analysis
Age (per year)1.007 (0.977 to 1.038)0.6471.011 (0.979 to 1.043)0.503
Sex (female)1.380 (0.797 to 2.388)0.2501.335 (0.723 to 2.464)0.356
Overweight/obesity1.337 (0.795 to 2.248)0.2731.209 (0.697 to 2.097)0.500
Hypertension1.009 (0.611 to 1.667)0.9720.966 (0.576 to 1.621)0.897
Poor glycemic control1.124 (0.685 to 1.844)0.6431.023 (0.609 to 1.718)0.932
High TG2.011 (1.200 to 3.369)0.0082.097 (1.199 to 3.670)0.009
Low HDL-C1.124 (0.685 to 1.843)0.6450.829 (0.464 to 1.482)0.527
Out of target for LDL-C1.390 (0.779 to 2.481)0.2641.541 (0.835 to 2.845)0.167

CI: confidence interval. Significant values (<0.05) are indicated in bold. Model 1: all the independent variables were analyzed separately; Model 2: all the independent variables were analyzed simultaneously. Significant values (<0.05) are indicated in bold.