Research Article
Attenuation of Diabetic Nephropathy in Diabetic Mice by Fasudil through Regulation of Macrophage Polarization
Figure 4
Fasudil increased M2 macrophage polarization and anti-inflammatory cytokines in renal tissues of diabetic mice. (a) Representative immunohistochemical staining of CD206 (a marker for M2 macrophages; red arrows) and IL-10 in renal tissues. (b) Quantitative analysis for the number of M2 macrophages in renal tissue specimens. Data are expressed as , vs. the Ctrl group; # vs. the DM group. (c) Quantitative analysis of the protein expression of IL-10 in renal tissue specimens. Data are expressed as , vs. the Ctrl group; # vs. the DM group.
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