Attenuation of Diabetic Nephropathy in Diabetic Mice by Fasudil through Regulation of Macrophage Polarization

Figure 5

Correlation between ROCK activity and macrophage polarization. (a) Western blot analysis of Arg-1, iNOS, p-MYTP1, and β-actin expression in renal tissue specimens. Data are expressed as of three independent experiments. (b–d) Quantification of Arg-1, iNOS, and p-MYTP1. The data are presented as the . vs. the Ctrl group; ^# vs. the DM group. (e) Western blot analysis of CD68 and β-actin expression in renal tissue specimens. Data are expressed as the of three independent experiments. (f) Correlation between p-MYTP1 and iNOS (, ). (g) Correlation between p-MYTP1 and Arg-1 (, ).

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