Association between Serum Ferritin and Blood Lipids: Influence of Diabetes and hs-CRP Levels
Table 4
Generalized linear model of the association between blood lipids and ferritin according to diabetes status.
Ferritin groups
value
<10.0 ng/mL
10.0-299.9 ng/mL
≥300.0 ng/mL
Mean
95% CI
Mean
95% CI
Mean
95% CI
Full model
Total
TG (mmol/L)
1.79
1.65-1.93
1.70
1.64-1.77
2.11
2.00-2.22
<0.0001
TC (mmol/L)
4.85
4.79-4.91
4.87
4.84-4.90
4.92
4.87-4.97
0.0833
HDL-C (mmol/L)
1.43
1.38-1.47
1.42
1.40-1.45
1.40
1.37-1.44
0.47
LDL-C (mmol/L)
2.93
2.84-3.00
2.97
2.94-3.00
2.85
2.80-2.90
<0.0001
Subjects without diabetes
TG (mmol/L)
1.62
1.50-1.74
1.54
1.50-1.58
1.91
1.82-2.01
<0.0001
TC (mmol/L)
4.81
4.75-4.86
4.84
4.83-4.86
4.89
4.84-4.93
0.0906
HDL-C (mmol/L)
1.45
1.41-1.49
1.45
1.44-1.47
1.44
1.41-1.48
0.7287
LDL-C (mmol/L)
2.95
2.89-3.00
3.00
2.98-3.01
2.88
2.83-2.92
<0.0001
Subjects with diabetes
TG (mmol/L)
2.05
0.96-3.14
2.38
2.19-2.56
2.86
2.56-3.16
0.0095
TC (mmol/L)
5.53
5.09-5.97
5.32
5.25-5.40
5.41
5.28-5.53
0.3157
HDL-C (mmol/L)
1.47
1.27-1.67
1.32
1.29-1.36
1.30
1.24-1.35
0.1891
LDL-C (mmol/L)
3.58
3.01-4.15
3.33
3.23-3.43
3.26
3.10-3.42
0.4631
Parsimonious model
Total
TG (mmol/L)
1.80
1.67-1.94
1.70
1.64-1.76
2.11
2.01-2.21
<0.0001
TC (mmol/L)
4.86
4.80-4.91
4.89
4.87-4.89
4.93
4.88-4.97
0.0915
HDL-C (mmol/L)
1.43
1.38-1.47
1.43
1.41-1.45
1.41
1.38-1.44
0.4836
LDL-C (mmol/L)
2.93
2.87-2.99
2.96
2.94-2.99
2.84
2.80-2.87
<0.0001
Subjects without diabetes
TG (mmol/L)
1.63
1.51-1.75
1.54
1.51-1.57
1.91
1.82-2.01
<0.0001
TC (mmol/L)
4.81
4.75-4.87
4.85
4.83-4.86
4.89
4.84-4.93
0.1103
HDL-C (mmol/L)
1.45
1.41-1.49
1.45
1.44-1.46
1.43
1.40-1.47
0.6878
LDL-C (mmol/L)
2.94
2.88-2.99
2.99
2.97-3.00
2.87
2.82-2.91
<0.0001
Subjects with diabetes
TG (mmol/L)
1.97
1.03-2.92
2.36
2.22-2.50
2.88
2.61-3.15
0.0026
TC (mmol/L)
5.47
5.06-5.87
5.34
5.28-2.40
5.40
5.29-5.51
0.5575
HDL-C (mmol/L)
1.42
0.99-1.84
1.32
1.26-1.38
1.37
1.25-1.49
0.7288
LDL-C (mmol/L)
3.45
3.02-3.88
3.29
3.22-3.35
3.17
3.05-3.30
0.195
Models based on lifestyle, demographic characteristics, clinical variables, and dietary factors were adjusted. The parsimonious model is adjusted to the same variables as the full model, except for some variables that deal with possible colinearity between certain covariates.
