The Effects of New Selective PPARα Agonist CP775146 on Systematic Lipid Metabolism in Obese Mice and Its Potential Mechanism

Figure 3

CP775146 alleviates hepatic damage induced by an HFD. H&E staining of liver sections (original magnification, 200x); /group. (a) Chow-fed group, (b) HFD-NC group, (c) HFD-CP775146 0.1 mg/kg group, and (d) HFD-CP775146 0.3 mg/kg group. (e) TG and (f) TC liver levels, (g) ALT levels, and (h) AST levels. (i, j) The mRNA expression levels of various genes. are shown (/group). (K1, K2) The protein expression levels of various genes. , , and vs. the chow-fed group; ^#, ^##, and ^### vs. HFD-NC group.

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