Research Article

Combined Effect of Maternal Vitamin D Deficiency and Gestational Diabetes Mellitus on Trajectories of Ultrasound-Measured Fetal Growth: A Birth Cohort Study in Beijing, China

Table 3

Separate and combined effects of maternal 25(OH)D deficiency and GDM on fetal growth trajectories.

PredictorsFetal growth assessed by EFW -scoreFetal growth assessed by AC -score
(%) with excessive fetal growthCrude ORAdjusted OR (%) with excessive fetal growthCrude ORAdjusted OR

No VDD, no GDM59282798 (47.2)ReferenceReference2686 (45.3)ReferenceReference
VDD without GDM27141359 (50.1)1.12 (1.02, 1.23)1.11 (1.00, 1.21)1272 (46.9)1.07 (0.97, 1.17)1.05 (0.95, 1.16)
GDM without VDD1637864 (52.8)1.25 (1.12, 1.40)1.15 (1.03, 1.29)852 (52.0)1.31 (1.17, 1.46)1.19 (1.06, 1.33)
Both VDD and GDM634358 (56.5)1.45 (1.23, 1.71)1.36 (1.15, 1.62)346 (54.6)1.45 (1.23, 1.71)1.32 (1.11, 1.56)

Abbreviations: AC: abdominal circumference; EFW: estimated fetal growth; CI: confidence interval; GDM: gestational diabetes mellitus; OR: odds ratio; VDD: maternal 25(OH)D deficiency.