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Journal of Diabetes Research
/
2020
/
Article
/
Tab 2
/
Research Article
Effect of Combination Therapy of Canagliflozin Added to Teneligliptin Monotherapy in Japanese Subjects with Type 2 Diabetes Mellitus: A Retrospective Study
Table 2
Changes of various parameters between baseline and 3 months later.
Parameters
Teneligliptin continued group
Canagliflozin add-on group
Δ
Body weight (kg)
<0.0001
Δ
BMI (kg/m
2
)
-0.9 ± 0.7
<0.0001
Δ
FPG (mg/dL)
0.0003
Δ
HbA1c (%)
<0.0001
Δ
Systolic BP (mmHg)
n.s.
Δ
Diastolic BP (mmHg)
n.s.
Δ
AST (U/L)
n.s.
Δ
ALT (U/L)
n.s.
Δγ
GTP (U/L)
0.03
Δ
Cre (mg/dL)
0.01
Δ
BUN (mg/dL)
0.001
Δ
eGFR (mL/min/1.73 m
2
)
0.04
Δ
Triglyceride (mg/dL)
n.s.
Δ
HDL cholesterol (mg/dL)
n.s.
Δ
LDL cholesterol (mg/dL)
n.s.
Δ
Uric acid (mg/dL)
0.02