Research Article

Effect of Combination Therapy of Canagliflozin Added to Teneligliptin Monotherapy in Japanese Subjects with Type 2 Diabetes Mellitus: A Retrospective Study

Table 2

Changes of various parameters between baseline and 3 months later.

ParametersTeneligliptin continued groupCanagliflozin add-on group

ΔBody weight (kg)<0.0001
ΔBMI (kg/m2)-0.9 ± 0.7<0.0001
ΔFPG (mg/dL)0.0003
ΔHbA1c (%)<0.0001
ΔSystolic BP (mmHg)n.s.
ΔDiastolic BP (mmHg)n.s.
ΔAST (U/L)n.s.
ΔALT (U/L)n.s.
ΔγGTP (U/L)0.03
ΔCre (mg/dL)0.01
ΔBUN (mg/dL)0.001
ΔeGFR (mL/min/1.73 m2)0.04
ΔTriglyceride (mg/dL)n.s.
ΔHDL cholesterol (mg/dL)n.s.
ΔLDL cholesterol (mg/dL)n.s.
ΔUric acid (mg/dL)0.02