Melatonin Alleviates Glucose and Lipid Metabolism Disorders in Guinea Pigs Caused by Different Artificial Light Rhythms

Figure 1

Effect of melatonin on food intake, water consumption, body weight, HOMA-IR, and fasting blood glucose and insulin levels. (a) Food intake, (b) water consumption, (c) body weight, (d) fasting blood glucose, (e) fasting insulin level, and (f) HOMA-IR. C: control group; H: HFD group; 12HL: 12 h light group; 24HL: 24 h light group; M: melatonin group. The values are expressed as the (–12 per group). ^#, ^##, and ^###, HFD vs. control; ^{^}, ^{^^}, and ^{^^^}, 12HL vs. HFD group; ^&, ^&&, and ^&&&, 24HL vs. 12HL group; , , and , M vs. 24HL group.

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