Melatonin Alleviates Glucose and Lipid Metabolism Disorders in Guinea Pigs Caused by Different Artificial Light Rhythms

Figure 2

Effect of melatonin on OGTT and ITT before or after treatment. (a) OGTT, (b) AUC of OGTT, (c) ITT, and (d) AUC of ITT before treatment (on week 6); (e) OGTT, (f) AUC of OGTT, (g) ITT, and (h) AUC of ITT after treatment (on week 10). C: control group; H: HFD group; 12HL: 12 h light group; 24HL: 24 h light group; M: melatonin group. The values are expressed as the (-12 per group). ^#, ^##, and ^###, HFD vs. control; ^{^}, ^{^^}, and ^{^^^}, 12HL vs. HFD group; ^&, ^&&, and ^&&&, 24HL vs. 12HL group; , , and , M vs. 24HL group.

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