Melatonin Alleviates Glucose and Lipid Metabolism Disorders in Guinea Pigs Caused by Different Artificial Light Rhythms

Figure 4

Effect of melatonin on endocrine hormones and inflammation. (a) Melatonin, (b) adiponectin, (c) leptin, (d) TNF-α, (e) IL-6, and (f) IL-1β after treatment (on week 10). C: control group; H: HFD group; 12HL: 12 h light group; 24HL: 24 h light group; M: melatonin group. The values are expressed as the (-8 per group). ^# and ^##, HFD vs. control; ^{^^}, 12HL vs. HFD group; ^&, ^&&, and ^&&&, 24HL vs. 12HL group; , , and , M vs. 24HL group.

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