Novel Indices of Glucose Homeostasis Derived from Principal Component Analysis: Application for Metabolic Assessment in Pregnancy

Table 2

Demographic characteristics of NGT subjects compared to GDM subjects.

		NGT		GDM	values
Age at enrollment (years)	61		6		<0.001
Primiparity (total/in % of )	61	41/67.2	6	4/66.6	0.978
Prepregnancy BMI (kg/m^2)	61		6		<0.001
History of GDM (total/in % of )	61	3/4.9	6	2/33.3	0.06
History of GDM (total/in % of ) in multiparous women	20	3/15.0	2	2/100.0	0.043
Family history with T2 diabetes (total/in % of )	60^#	20/33.3	6	3/50	0.413
G0 at V1 (mg/dl)	61		6		<0.001
G60 at V1 (mg/dl)	61		6		<0.001
G120 at V1 (mg/dl)	61		6		<0.001

Data are expressed as or counts and percentages of BMI: body mass index; NGT: normal glucose tolerance; GDM: gestational diabetes mellitus; T2 diabetes: type 2 diabetes mellitus. G0, G60, and G120 are glucose values for fasting and 60 and 120 minutes after oral glucose load at V1 (first visit, 12 to 22 weeks of gestation). Natural log transformation. ^#One patient was adopted, family history not available.