IgG Glycosylation Profile and the Glycan Score Are Associated with Type 2 Diabetes in Independent Chinese Populations: A Case-Control Study

Table 1

The characteristics of participants in the discovery and replication populations.

	Overall	Controls	Type 2 diabetes	value
Discovery population
Age (years)^a	51.40 (±7.65)	51.39 (±7.35)	51.41 (±7.97)	0.997
Sex (male/female)^b	72/252	36/126	36/126	1.000
BMI (<18.5/18.5~23.9/>23.9)^b	1/69/254	0/35/127	1/34/127	0.602
HBP (yes/no)^b	101/223	55/107	46/116	0.337
HDL-cholesterol (mmol/L)^c	1.13 (1.10-1.57)	1.45 (1.25-1.65)	1.19 (1.04-1.37)	<0.001
nonHDL-cholesterol (mmol/L)^c	3.50 (2.92-4.10)	3.62 (3.06-4.15)	3.29 (2.75-3.95)	0.007
Replication population
Age (years)^a	49.92 (±7.75)	42.15 (±9.77)	64.00 (±6.73)	<0.001
Sex (male/female)^b	338/450	91/417	247/33	<0.001
BMI (<18.5/18.5 ~ 23.9/>23.9)^b	26/318/444	26/277/205	0/41/239	<0.001
HBP (yes/no)^b	144/644	58/450	86/194	<0.001
HDL-cholesterol (mmol/L)^c	1.53 (1.25-1.79)	1.68 (1.47-1.86)	1.21 (1.04-1.44)	<0.001
nonHDL-cholesterol (mmol/L)^c	3.22 (2.64-3.76)	3.30 (2.84-3.83)	2.98 (2.29-3.58)	<0.001

^aMean (±SD) is given; ^bnumbers of each category are given; ^cmedian (P₂₅-P₇₅) is given.