ADIPOQ rs2241766 Gene Polymorphism and Predisposition to Diabetic Kidney Disease

Table 1

Main characteristics of the included studies in the present meta-analysis.

First author (year)	Country	Ethnicity	Control source	Type	Sample size	Case genotype			Control genotype			Genotyping method	NOS score	P(HWE)
					Case/control	TT	TG	GG	TT	TG	GG
Blech (2011)	Israel	Caucasian	Diabetic	T2DM or T1DM	852/1473	532	283	37	966	454	53	PCR-RFLP	7	0.999
Choe (2013)	Korea	Asian	Diabetic	T2DM	245/448	124	95	26	216	204	28	SNaPShot	7	0.083
Chung (2014)	China	Asian	Diabetic	T2DM	144/422	77	57	10	206	186	30	Multiplex PCR	8	0.386
El-Shal (2014)	Egypt	African	Diabetic	T2DM	196/100	53	113	30	64	32	4	PCR-RFLP	7	1
Jaziri (2010)	France	Caucasian	Diabetic	T2DM	75/3011	46	25	4	2223	728	60	PCR-MB	8	0.999
Ma (2007)	Sweden	Caucasian	Diabetic	T1DM	196/236	180	15	1	213	22	1	PCR-DASH	7	0.871
Peng (2012)	China	Asian	Diabetic	T2DM	42/40	25	14	3	19	18	3	DS	7	0.903
Ranjbar (2011)	Iran	Caucasian	Diabetic	T2DM	28/205	20	8	0	142	56	7	PCR-RFLP	7	0.880
Rudofsky (2004)	Germany	Caucasian	Diabetic	T1DM	73/166	47	26		147	19		PCR-RFLP	8	N/A
Rudofsky (2004)	Germany	Caucasian	Diabetic	T2DM	174/283	137	37		239	44		PCR-RFLP	8	N/A
Sikka (2014)	India	Asian	Diabetic	T2DM	145/152	124	20	1	128	22	2	PCR-RFLP	6	0.654
Vionnet (2006)	Denmark	Caucasian	Diabetic	T1DM	489/463	393	91	5	377	82	4	Ampli-Fluor	7	0.981
Vionnet (2006)	Finland	Caucasian	Diabetic	T1DM	387/469	349	37	1	416	51	2	Ampli-Fluor	7	0.949
Vionnet (2006)	France	Caucasian	Diabetic	T1DM	300/391	221	73	6	303	82	6	Ampli-Fluor	7	0.986

PCR: polymerase chain reaction; PCR-RFLP: PCR-restriction fragment length polymorphism; PCR-MB: PCR-molecular beacon; PCR-DASH: PCR-dynamic allele-specific hybridization; DS: Direct sequencing.