Gene Expression Profiling of the Sciatic Nerve in Streptozotocin-Induced Diabetic Rats with Peripheral Neuropathy

Figure 5

GO and KEGG pathway enrichment analyses based on the 597 DEGs. GO and KEGG pathway enrichment analyses demonstrated that 4 BP items (“response to drug,” “positive regulation of cell proliferation,” “fatty acid metabolic process,” and “organ regeneration”), 10 CC items (“extracellular space,” “extracellular exosome,” “endoplasmic reticulum membrane,” “endoplasmic reticulum,” “cell surface,” “cytoplasm,” “perinuclear region of cytoplasm,” “membrane,” “condensed chromosome kinetochore,” and “proteinaceous extracellular matrix”), 1 MF item (“protein homodimerization activity”), and 2 KEGG items (“glycerolipid metabolism” and “metabolic pathways”) were enriched for the combined 597 DEGs.