Change in Viability and Function of Pancreatic Islets after Coculture with Mesenchymal Stromal Cells: A Systemic Review and Meta-Analysis

Table 2

Meta-analysis of islet viability and ISI in subgroups.

Outcome	Subgroup	Studies	Meta-analysis			(%)
			Mean difference	95% CI
Viability	Direct coculture	12	-19.82	-26.56~-13.07	<0.00001	89
	Indirect coculture	4	-1.14	-7.82~5.54	0.74	74
ISI	Direct coculture	21	-2.42	-3.94~-0.89	0.002	99
	Indirect coculture	9	-2.54	-4.79~-0.28	0.03	99

Note. ISI = insulin stimulation index; CI = confidence interval.