Change in Viability and Function of Pancreatic Islets after Coculture with Mesenchymal Stromal Cells: A Systemic Review and Meta-Analysis

Table 4

Characteristics of studies included in the meta-analysis that performed islet transplantation in vivo.

Author [reference]	Year	Outcome evaluated	Number of transplantation cell		Encapsulation	Transplantation site	Islet origin	Recipient origin
			Islet	MSCs
Davis et al. [27]	2012	IPGTT	600 IEQ	600	Yes	Peritoneal cavity	SD rat	Balb/C mouse
Karaoz et al. [29]	2011	FBG	350 IEQ	450-500	Yes	Peritoneal cavity	C57BL/6J	C57BL/6J
Ayenehdeh et al. [20]	2017	FBG	100 IEQ		No	Peritoneal cavity	Balb/C	C57BL/6
Montanari et al. [15]	2017	IPGTT	4500–5000 IEQ	450-500	Yes	Peritoneal cavity	Human	C57BL/6 mouse
Rackham et al. [14]	2013	FBG, IPGTT	100 IEQ		No	Underneath the kidney capsule	C567BL/6	C567BL/6
Ren et al. [21]	2019	FBG	150–225IEQ		No	Underneath the kidney capsule	C57BL/6	C57BL/6
Yamada et al. [36]	2014	FBG, IPGTT	1500 IEQ		Yes	Peritoneal cavity	Wistar rat	Balb/C mouse
Yoshimatsu et al. [9]	2015	FBG, IPGTT	500 IEQ		No	Femur muscle	Balb/C	Balb/C

Note. FBG = fasting blood glucose; IPGTT = intraperitoneal glucose tolerance test; IEQ = islet equivalent.