Enterotype Bacteroides Is Associated with a High Risk in Patients with Diabetes: A Pilot Study

Table 1

Characteristics of T2D and control groups.

Parameters	Control group	T2D group	value
Age (year)	50.00 (45.00, 57.50)	59.50 (50.27, 66.64)	<0.001
BMI (kg/m^2)	25.84 (23.10, 27.17)	25.39 (23.49, 27.51)	0.896
SBP (mmHg)	133 (120, 147)	131.25 (123.00, 145.50)	0.912
DBP (mmHg)	81.80 ± 11.31	75.85 ± 10.52	0.004
HbA1c (%)	5.10 (4.90, 5.40)	8.40 (7.30, 9.70)	<0.001
FPG (mmol/L)	5.30 (5.20, 5.50)	7.57 (6.31, 8.95)	<0.001
FINS (uIU/ml)	6.85 (4.29, 8.99)	10.72 (5.97, 19.77)	<0.001
FCP (ng/ml)	1.19 (0.96, 1.58)	1.21 (0.86, 2.01)	0.535
2hPG (mmol/L)	5.60 (5.23, 7.45)	16.96 (14.60, 18.41)	<0.001
2hINS (uIU/ml)	20.81 (15.53, 35.11)	38.40 (22.63, 54.57)	<0.001
2hCP (ng/ml)	4.62 (4.08, 8.00)	3.87 (2.56, 5.39)	0.001
HDL-C (mmol/L)	1.55 (1.38, 1.85)	1.20 (1.02, 1.41)	<0.001
TG (mmol/L)	1.04 (0.77, 1.38)	1.38 (1.00, 1.92)	0.001
Gutt-ISI	0.54 (0.42, 0.65)	0.20 (0.17, 0.25)	<0.001
HOMA-β (CP)	77.00 (61.70, 90.50)	41.45 (26.60, 63.75)	<0.001
HOMA-IR (CP)	0.89 (0.74, 1.19)	1.05 (0.70, 1.68)	0.100

The normal distribution of the data was tested using the Kolmogorov-Smirnov test. Values are expressed as median (interquartile range; abnormal distribution) and (normal distribution). Differences between groups were detected using a Student’s test (normal distribution) or Mann–Whitney test (abnormal distribution). T2D: type 2 diabetes; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1c: glycated hemoglobin; FPG: fasting plasma glucose; FINS: fasting insulin; FCP: fasting C peptide; 2hPG: 2-hour postprandial plasma glucose; 2hINS: 2-hour postprandial plasma insulin; 2hCP: 2-hour postprandial C peptide; HDL-C: high-density lipoprotein cholesterol; TG: triglyceride levels; Gutt-ISI: Gutt-insulin sensitivity index; HOMA-β: homeostasis model assessment of β-cell function; HOMA-IR: homeostasis model assessment of insulin resistance. .