Research Article

The Relationship between Perirenal Fat Thickness and Reduced Glomerular Filtration Rate in Patients with Type 2 Diabetes

Table 1

Characteristics of the overall study population and of the population divided into three groups based on PrFT.

TotalPrFT1 (<0.6 cm)PrFT2 (0.6-1.33 cm)PrFT3 (≥1.33 cm)

Sex (men/women)81/9012/3242/4427/140.002
Age (year)0.625
Diabetes duration (year)10 (3­15)12 (3.25­16.75)8 (3­13)12 (3­20)#0.034
BMI (kg/m2)#<0.001
WC (cm)#<0.001
FPG (mmol/l)0.519
UA (μmol/l)#0.008
TG (mmol/l)1.44 (1.05­2.04)1.15 (0.84­1.77)1.44 (1.20­2.06)1.75 (1.24­2.85)0.004
TC (mmol/l)0.133
HDL-c (mmol/l)<0.001
LDL-c (mmol/l)0.306
HbA1c (%)0.051
VFA (cm2)##<0.001
PnFT (cm)##<0.001
PrFT (cm)##<0.001
UACR (mg/g)9.18 (3.91­41.94)9.59 (3.80­26.42)8.58 (3.39­41.23)9.29 (4.83­67.28)0.663
eGFR (ml/min/1.73 m2)0.026

BMI: body mass index; WC: waist circumference; FPG: fast plasma glucose; UA: uric acid; TG: triglyceride; TC: total cholesterol; HDL-c: high-density lipoprotein-cholesterol; LDL-c: low-density lipoprotein-cholesterol; HbA1c: glycated hemoglobin; VFA: visceral fat area; PnFT: paranephric fat thickness; PrFT: perirenal fat thickness; UACR: urinary albumin creatinine ratio; eGFR: estimated glomerular filtration rate. PrFT1 vs. PrFT2: , . PrFT1 vs. PrFT3: , . PrFT2 vs. PrFT3: #, ##.