Research Article

Low Bone Turnover Markers in Young and Middle-Aged Male Patients with Type 2 Diabetes Mellitus

Table 1

Comparison of characteristics between diabetic patients and controls.

VariablesPatients with T2DM ()Nondiabetic controls ()

Age (y)0.285
Diabetic duration (y)4.0 (1.0, 9.0)
Height (cm)0.220
Weight (kg)0.097
BMI (kg/m2)0.294
SBP (mmHg)0.347
DBP (mmHg)0.470
FBG (mmol/l)<0.001
HbA1c (%)
INS (mIU/l)9.28 (5.32, 13.73)
C-P (ng/ml)1.59 (1.15, 2.16)
TG (mmol/l)2.32 (1.42, 3.23)1.22 (0.85, 1.86)<0.001
TC (mmol/l)<0.001
HDL-c (mmol/l)0.020
LDL-c (mmol/l)<0.001
Ca (mmol/l)0.193
P (mmol/l)0.118
TP (g/l)0.897
ALB (g/l)0.825
ALT (IU/l)0.782
AST (IU/l)0.554
ALP (IU/l)0.410
Cr (μmol/l)0.639
SUA (μmol/l)0.932
BUN (mmol/l)0.641

y: years; T2DM: type 2 diabetes mellitus; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FBG: fasting blood glucose; HbA1c: haemoglobin A1c; INS: fasting insulin; C-P: fasting C-peptide; TG: triglyceride; TC: total cholesterol; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol; Ca: calcium; P: phosphorus; TP: total protein; ALB: albumin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; Cr: serum creatinine; SUA: serum uric acid; BUN: blood urea nitrogen. value < 0.05 was considered significant.