Journal of Diabetes Research

Research Article

Impaired Glomerular Filtration Rate in Type 2 Diabetes Mellitus Subjects: A Nationwide Cross-Sectional Study in Thailand

Table 5

Univariate and multivariate logistic regression analysis to determine impaired GFR among patients with T2DM.


Factors	Univariate analysis		Multivariate logistic regression analysis
	Odd ratio (95% CI)	value	Odd ratio (95% CI)	value

Female	1.15 (1.09, 1.20)	<0.001	0.86 (0.51, 1.45)	0.564
Age (years)	1.09 (1.08, 1.09)	<0.001	1.09 (1.07, 1.12)	<0.001
BMI (kg/m²)	0.95 (0.94, 0.95)	<0.001	0.98 (0.93, 1.02)	0.326
Smoking (yes)	0.90 (0.84, 0.96)	0.002	1.01 (0.51, 1.99)	0.987
Systolic BP (mmHg)	1.02 (1.02, 1.02)	<0.001	1.02 (1.00, 1.04)	0.030
Diastolic BP (mmHg)	0.97 (0.96, 0.97)	<0.001	0.98 (0.96, 1.01)	0.311
HemoglobinA1C (%)	0.98 (0.97, 0.99)	0.001	1.16 (1.04, 1.31)	0.009
Hemoglobin (g/dL)	0.69 (0.68, 0.71)	<0.001	0.85 (0.74, 0.98)	0.029
Serum uric acid (mg/dL)	1.42 (1.38, 1.46)	<0.001	1.90 (1.64, 2.20)	<0.001
Total cholesterol (mg/dL)	1.01 (1.01, 1.02)	<0.001	1.00 (0.99, 1.01)	0.966
Triglycerides (mg/dL)	1.01 (1.01, 1.02)	<0.001	1.01 (0.99, 1.02)	0.144
HDL-cholesterol (mg/dL)	0.99 (0.98, 0.99)	<0.001	1.00 (0.99, 1.01)	1.000
UACR (mg/gCr)	1.01 (1.01, 1.02)	<0.001	1.01 (1.01, 1.02)	0.045

Abbreviation: BP: blood pressure; BMI: body mass index; UACR: urine albumin creatinine ratio.
^aAdjusted by age, sex, BMI, waist circumference, smoking, systolic BP, diastolic BP, HA1C, hemoglobin, serum uric acid, triglycerides, HDL-cholesterol, and albuminuria.