Potential Role of Gene Regulator NFAT5 in the Pathogenesis of Diabetes Mellitus

Table 1

Diabetes-associated intronic single-nucleotide polymorphisms in NFAT5 [6–10].

SNP	Allele	Position on Chr16	Trait
rs17297179	A	69607827	eGFR
rs1064825	G	69690317	eGFR
rs17297207	A	68200854	Persistent proteinuria (>0.5 g/day) >10 years with T1DM
rs862320	C	69651866	T2DM

Chr16: chromosome 16; eGFR: estimated glomerular filtration rate; SNP: single-nucleotide polymorphism; T1DM: type 1 diabetes mellitus; T2DM: type 2 diabetes mellitus.