20(S)-Ginsenoside Rg3 Protects Kidney from Diabetic Kidney Disease via Renal Inflammation Depression in Diabetic Rats

Figure 1

The experimental design and animal experiment flow chart. Four-week-old male Wistar rats were fed high-fat and high-sugar diets. After feeding for 4 weeks, the rats were given an intraperitoneal injection of STZ (0.1 mmol/L sodium citrate buffer, pH 4.4, 35 mg/kg body weight) once, followed by a high-fat and high-sugar diet for 1 week for diabetic model. FBG above 16.7 mmol/L continuously was considered successful modeling. The rats were randomly assigned to three groups after establishment of the diabetic model. Give saline or 20(S)-Rg3 intervention for 12 weeks. Body weight and other indicators were tested.