Total Bilirubin Predicts Severe Progression of Diabetic Retinopathy and the Possible Causal Mechanism

Table 2

Characterization of DR individuals in an outpatient visit.

Group	Progression group ()	Stable group ()	// value	value
Gender (male/female)	9/14	53/52	0.972	0.324
Age (year)			0.367	0.714
Average follow-up time (month)	50 (39–55)	49 (37–54)	0.269	0.835
Duration of diabetes (year)			0.937	0.351
Type of diabetes (T1DM/T2DM)	6/17	28/77	0.003	0.955
ALT (IU/l)	21 (13–39)	19 (14–33)	0.943	0.316
TBIL (μmol/l)			6.147	<0.001
Γ-GT (IU/l)	21.5 (10–36)	19 (12–35)	1.845	0.124
Cr (μmol/l)	91 (45–106)	87 (42–104)	1.654	0.189
eGFR			0.468	0.640
FPG (mmol/l)			1.850	0.067
HbA1c (%)			0.55	0.583
Urobilinogen (mg/dl)	0.75 (0.23–1.04)	0.48 (0.05–0.67)	5.568	<0.001
LPS (Eu/ml)	0.71 (0.34–1.79)	0.58 (0.20–1.45)	2.263	0.037