Radix Rehmanniae and Corni Fructus against Diabetic Nephropathy via AGE-RAGE Signaling Pathway

Table 1

Active compounds of RR and CF.

No.	Molecule ID	Molecule name	OB (%)	DL	Herb
1	MOL001494	Mandenol	42	0.19	CF
2	MOL001495	Ethyl linolenate	46.1	0.2	CF
3	MOL001771	Poriferast-5-en-3beta-ol	36.91	0.75	CF
4	MOL002879	Diop	43.59	0.39	CF
5	MOL002883	Ethyl oleate (NF)	32.4	0.19	CF
6	MOL003137	Leucanthoside	32.12	0.78	CF
7	MOL000358	Beta-sitosterol	36.91	0.75	CF
8	MOL000358	Sitosterol	36.91	0.75	CF, RR
9	MOL000449	Stigmasterol	43.83	0.76	CF, RR
10	MOL005360	Malkangunin	57.71	0.63	CF
11	MOL005481	2,6,10,14,18-Pentamethylicosa-2,6,10,14,18-pentaene	33.40	0.24	CF
12	MOL005486	3,4-Dehydrolycopen-16-al	46.64	0.49	CF
13	MOL005489	3,6-Digalloylglucose	31.42	0.66	CF
14	MOL005503	Cornudentanone	39.66	0.33	CF
15	MOL005530	Hydroxygenkwanin	36.47	0.27	CF
16	MOL005531	Telocinobufagin	69.99	0.79	CF
17	MOL008457	Tetrahydroalstonine	32.42	0.81	CF
18	MOL000554	Gallic acid-3-O-(6-O-galloyl)-glucoside	30.25	0.67	CF
19	MOL005552	Gemin D	68.83	0.56	CF
20	MOL005557	Lanosta-8,24-dien-3-ol,3-acetate	44.30	0.82	CF
21	MOL005499	Morroniside	3.98	0.50	CF
22	MOL001680	Loganin	5.90	0.44	CF
23	MOL000511	Ursolic acid	16.77	0.75	CF
24	MOL000414	Caffeic acid	54.97	0.05	CF
25	MOL000263	Oleanolic acid	29.02	0.76	CF
26	MOL002819	Catalpol	5.07	0.44	RR
27	MOL003333	Acteoside	2.94	0.62	RR
28	MOL000519	Coniferin	31.11	0.32	RR
29	MOL000842	Sucrose	7.17	0.23	RR

Abbreviations: CF: Corni Fructus; RR: Radix Rehmanniae; OB: oral bioavailability; DL: drug-likeness.