Research Article

Reduced Birth Weight, Decreased Early-Phase Insulin Secretion, and Increased Glucose Concentrations after Oral Glucose Tolerance Test in Japanese Women Aged 20 Years with Family History of Type 2 Diabetes

Table 2

Glucose and insulin responses during 75 g oral glucose tolerance tests of young women in the presence and absence of family history of type 2 diabetes (FHD).

Positive FHDNegative FHD values

Fasting glucose (mg/dL)0.572
2 h glucose (mg/dL)0.029
Fasting insulin (μU/mL)0.653
2 h insulin (μU/mL)0.068
Matsuda index0.925
Insulinogenic indexa0.007
Disposition indexa0.008
AUCg0.006
AUCi0.382
AUCi/AUCg0.711
Athletes (, %)9, 15.8%32, 33.3%0.023

Mean ± SD or , %. AUCg and AUCi: area under the concentration curve of plasma glucose and serum insulin, respectively. aLogarithmically transformed.