Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes

Figure 6

Effect of diabetes and insulin treatment on sciatic nerve (a) sorbitol and (b) myo-inositol contents. Data are presented as mean and SD. and , significantly different from control. ⁺ and ⁺⁺⁺, significantly different from STZ-DIO high-insulin. Control, ; STZ-DIO vehicle, ; STZ-DIO low-insulin, ; STZ-DIO high-insulin, except in cases where indicated otherwise, A: ; B: ; C: .

(a)

(b)