Restoration of Foveal Bulge after Resolution of Diabetic Macular Edema with Coexisting Serous Retinal Detachment

Table 2

Comparison of posttreatment optical coherence tomography measurements in diabetic macular edema eyes with coexisting serous retinal detachment in foveal bulge (+) group and foveal bulge (-) group.

	Foveal bulge (+) ()	Foveal bulge (-) ()
IVR (SD) (n)	4.00 (1.29)	4.19 (1.18)	0.460^†
Mean 6M BCVA (SD) (LogMAR/Snellen VA)	0.19 (0.18)/≈20/31.0	0.35 (0.18)/≈20/44.8	0.004^†
Mean 6M CFT (SD) (μm)	187.68 (27.00)	196.37 (29.54)	0.314^†
Mean ONL thickness (SD) (μm)	94.80 (15.53)	101.67 (18.17)	0.203^†
Mean photoreceptor IS length (SD) (μm)	31.28 (2.76)	30.70 (3.45)	0.289^†
Mean photoreceptor OS length (SD) (μm)	41.48 (3.39)	31.44 (3.24)	<0.001^†
SRD complete resolution ( (%))
1 M	21 (84.0%)	13 (48.1%)	0.009^‡
3 M	24 (96.0%)	18 (66.7%)	0.012^‡

^†Unpaired Mann-Whitney test; ^‡Fisher’s exact test. IVR: intravitreal injection of ranibizumab; 6 M: 6 months after 3 monthly consecutive intravitreal injections of ranibizumab treatment; BCVA: best-corrected visual acuity; Snellen VA: Snellen visual acuity; CFT: central foveal thickness; ONL: outer nuclear layer; IS: inner segment; OS: outer segment; SD: standard deviation; SRD: serous retinal detachment.