Polymorphisms in Genes of Lipid Metabolism Are Associated with Type 2 Diabetes Mellitus and Periodontitis, as Comorbidities, and with the Subjects’ Periodontal, Glycemic, and Lipid Profiles
Table 1
Information regarding the 14 investigated single-nucleotide polymorphisms (SNPs) in lipid metabolism genes.
SNP
Assay ID
SNP position†, alleles
Gene and classification of mutation
Call rate (%)
rs5925
C___2804279_10
chr19:g.11230881T>C
LDLR (silent mutation)
96.92
rs688
C___2804264_20
chr19:g.11227602C>T
LDLR (silent mutation)
96.36
rs676210
C___3216558_10
chr11:g.21231524G>A
APOB (missense mutation)
95.66
rs1042031
C___7615381_20
chr11:g.21225753C>T
APOB (silent mutation)
96.22
rs693
C___7615420_20
chr11:g.21232195G>A
APOB (silent mutation)
96.92
rs6544718
C__25642779_10
chr2:g.44104925T>A
ABCC8 (missense variant)
97.21
rs6544713
C__26135636_10
chr2:g.44073881T>C
ABCC8 (intron variant)
97.35
rs285
C__12104266_10
chr8:g.19815189C>T
LPL (intron variant)
96.65
rs3735964
C__25800209_10
chr8:g.19824045C>A
LPL (3 prime UTR variant)
96.51
rs13702
C___9639448_10
chr8:g.19824492T>A
LPL (3 prime UTR variant)
90.08
rs2650000
C__15874272_10
chr12:g.121388962A>C
HNF1A (intragenic)
96.51
rs429358
C___3084793_20
chr19:g.45411941T>C
APOE (missense variant)
97.35
rs7412
C____904973_10
chr19:g.45412079C>T
APOE (missense variant)
97.35
rs1800961
C___7591528_10
chr20:g.43042364C>T
HNF4A (missense variant)
96.51
†Genome Reference Consortium Human Build 37 (GRCh37.p13) or hg19. Represents the percentage of genotyping performed with success (all subjects).
