Research Article

Liraglutide Decreases Liver Fat Content and Serum Fibroblast Growth Factor 21 Levels in Newly Diagnosed Overweight Patients with Type 2 Diabetes and Nonalcoholic Fatty Liver Disease

Table 2

Associations between FGF21 and various factors at baseline in all subjects.


Age-0.2520.121
Weight0.0320.848
BMI0.0880.596
Waist circumference0.2320.156
FBG0.575<0.001
2 hPBG0.5150.001
FINS0.808<0.001
HOMA-IR0.788<0.001
HbA1c0.857<0.001
TCH0.3890.014
HDL-0.3830.016
LDL0.1360.408
TG0.2860.078
ALT0.649<0.001
AST0.591<0.001
ALP0.1890.250
GGT0.537<0.001
Liver fat content0.717<0.001

Abbreviations: BMI: body mass index; FBG: fasting blood glucose; 2 hPBG: 2-hour postprandial blood glucose; FINS: fasting insulin; HOMA-IR: homeostasis model assessment of insulin resistance; HbA1c: glycated hemoglobin; TC: total cholesterol; HDL: high-density lipoprotein cholesterol; TG: triglyceride; LDL: low-density lipoprotein cholesterol; ALT: alanine amino transferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; GGT: γ-glutamyl transferase; FGF21: fibroblast growth factor 21. ; .