Research Article

Trends in the Use of Sphingosine 1 Phosphate in Age-Related Diseases: A Scientometric Research Study (1992-2020)

Table 2

Top 10 most cited articles.

TitleInstitutionsFirst authorJournalPublication yearIF (2019)Total citations

Principles of bioactive lipid signalling: lessons from sphingolipidsMedical University of South Carolina, USAHannun, Yusuf A.Nature Reviews Molecular Cell Biology200843.351884
A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosisUniversity of Basel, SwitzerlandKappos, LudwigNew England Journal of Medicine201070.671565
Bioactive sphingolipids: metabolism and functionMedical University of South Carolina, USABartke, NanaJournal of Lipid Research20094.74368
Deregulation of sphingolipid metabolism in Alzheimer’s diseaseMount Sinai School of Medicine, USAHe, XingxuanNeurobiology of Aging20104.39252
Sphingolipids in mammalian cell signallingUniversity of Manchester, UKOhanian, JCellular and Molecular Life Sciences20017.01183
Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistanceMedical University of South Carolina, USAPonnusamy, SuriyanFuture Oncology20102.27182
Sphingosine-1-phosphate produced by Sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesisVirginia Commonwealth University School of Medicine, USANagahashi, MasayukiCancer Research20128.37163
How to preserve fertility in young women exposed to chemotherapy? The role of GnRH agonist cotreatment in addition to cryopreservation of embrya, oocytes, or ovariesRambam Medical Center, Technion-Faculty of Medicine, IsraelBlumenfeld, ZeevOncologist20075.25162
Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trialMount Sinai School of Medicine, USA, etc.Lublin, FredLancet201659.10156
Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 studyUniversity of Basel, Switzerland, etc.Kappos, LudwigLancet201859.10150