Diabetic Peripheral Neuropathy in Ethiopia: A Systematic Review and Meta-Analysis

Table 1

Characteristics of studies included in the systematic review and meta-analysis of the prevalence of DPN among adult patients with diabetes in Ethiopia, 2020.

Author	Publication year	Data collection year	Study region	Types of hospital	Types of DM	SD	Sample size			Number of patients with DPN by type of DM			Prevalence (%)	Methods for detecting DPN	Quality assessment (based on NOS)
							Type I	Type II	Total	Type I	Type II	Total
Worku et al. [15]	2010	October 2008	Oromia	Referral	Types I and II	CS	116	189	305	19	71	90	29.5	MNSI assessment	8
Gudina et al. [16]	2011	From August to November 2009	Oromia	Referral	Types I and II	CS	117	212	329	NM	NM	27	8.2	DNS instrument	7
Ejigu [17]	2000	September 1996 to July 1997	AA	Referral	Types I and II	RDS	112	171	283	25	75	100	35.3	DNE instrument	9
Tsehay et al. [18]	2014	From May to June 2014	AA	Referral	Type II	CS			321		73	73	22.7	DNE instrument	7
Abejew et al. [19]	2015	From April to May 2013	Amhara	Referral	Types I and II	CS	NM	NM	216	NM	NM	13	6	DNS instrument	6
Gizaw et al. [20]	2015	Between January 2010 and December 2013	AA	Referral	Types I and II	RDS	122	401	523	20	89	109	20.8	DNE instrument	8
Feleke and Enquselassie [21]	2005	From February 2002 to July 2003	AA	Mixed	Types I and II	CS	50	179	229	NM	NM	20	10	DNE instrument	7
Wild et al. [22]	2000	1993	Different regions	Mixed	Type II	CS	—	1386	1386	—	146	146	10.5	MNSI assessment	8
Gebre and Assefa [23]	2019	From April 1 to April 2019	SNNPR	General	Types I and II	CS	160	178	338	NM	NM	50	14.8	NSS, NDS	7
Korsa et al. [24]	2019	Between March and April 2016	Oromia	Mixed	Types I and II	CS	148	109	257	NM	NM	8	3.11	NSS, NDS	6
Lebeta et al. [25]	2017	From April to May 2015	Amara	Referral	Type II	CS	—	344	344	—	344	27	7.8	NSS, NDS	9
Ahmed et al. [26]	2018	From July to August 2015	Oromia	Referral	Types I and II	CS	70	90	160	NM	NM	10	6.3	DNS instrument	7
Fiseha and Belete[27]	2018	From January 2008 to August 2015	SNNPR	Referral	Types I and II	CO	187	495	682	NM	NM	116	17	DNS instrument	8
Jember et al. [9]	2017	From February 2016 to June 30 2016	Amara	Referral	Types I and II	CS	164	204	368	84	108	192	52.2	DNS instrument	8
Tilahun et al. [28]	2017	October to December of 2015	Oromia	Referral	Types I and II	CS	98	138	236	NM	NM	60	25.4	NSS, NDS	7
Tesfaye [29]	2014	From October to November 2013	AA	Referral	Types I and II	CS	56	191	247	NM	NM	25	10.1	Clinical examination	6
Jarso et al. [30]	2011	December 2009 to February 2010	AA	Referral	Types I and II	CS	104	280	384	86	99	185	48.2	DNS instrument	9
Lester [31]	1984	1982	AA	Referral	Types I and II	CS	NM	NM	849	NM	NM	235	27.8	DNS instrument	8
Fiseha and Belete [27]	2011	2010	AA	Referral	Types I and II	CS	NM	NM	724	NM	NM	90	12.4	Clinical examination	9
Gill et al. [32]	2008	2007	AA	Referral	Types I and II	CS	NM	NM	108	NM	NM	43	41	Clinical examination	7
Fasil et al. [33]	2019	February–March 2017	Amara	Referral	Types I and II	CS	NM	NM	367	NM	NM	29	7.9	DNS assessment	8
Lester [34]	1983	1983	AA	Referral	Types I and II	CS	NM	NM	809	NM	NM	47	5.8	DNE instrument	7
Lester et al. [35]	1976	1976	AA	Referral	Types I and II	CS	NM	NM	404	NM	NM	38	9.4	DNS assessment	6
Teshager [36]	2016	March–April 2016	Amhara	Referral	Types I and II	CS	178	238	416	NM	NM	14	3.4	DNS assessment	9
Kefeany [37]	2017	March–May 2017	AA	Referral	Type II	CS	—	121	121	—	49	49	40.5	NSS, NDS	8
Kassahun et al. [38]	2016	February–April 2014	Oromia	Referral	Type II	CS	—	309	309	—	146	146	47.2	DNE instrument	8
Eticha et al. [39]	2016	February 2015	Tigray	Referral	Type II	CS	—	384	384	—	125	125	32.6	NSS, NDS	7
Cheneke et al. [40]	2016	From May to July 2012	Oromia	Referral	Types I and II	CS	NM	NM	148	NM	NM	18	12.2	Clinical examination	6
Shiels et al. [8]	2018	From October 2016 to January 2017	AA	Referral (police)	Type II	CS	—	414	414	—	8	8	1.9	NSS, NDS	8
Mariam et al. [41]	2017	From March to April 2016	Amhara	Referral	Types I and II	CS	110	169	279	NM	NM	28	10	NSS, NDS	7
Demoz et al. [42]	2019	From August 2017 to July 2018	AA	Referral	Type II	CS	—	357	357	—	167	167	46.8	Clinical examination	7
Yigazu and Deese [43]	2017	From February to March 2016	Oromia	General	Type II	CS	—	174	174	—	31	31	17.8	Clinical examination	8
Woldu et al. [44]	2018	March 2017	Amhara	Referral	Type II	CS	—	341	341	—	64	64	18.8	DNE instrument	9
Abdissa et al. [45]	2019	June to August 2019	Oromia	Referral	Types I and II	CS	48	229	277	NM	NM	129	46.6	NSS, NDS	9
Tamura et al. [46]	2020	March 1 to April 28, 2019	AA	Referral	Type II	CS	—	346	346	—	53	53	15.3	MNSI assessment	7
Abdissa et al. [47]	2020	September to November 2019	Oromia	Referral	Type II	CS	—	336	336	—	196	196	53.6	DNS instrument	8
Woldemariam et al. [48]	2020	March to May 2019	AA	Referral	Types I and II	CS	NM	NM	161	NM	NM	44	27.3	DNE instrument	9
YimamAhmed et al. [49]	2020	February to March 2019	Oromia	Referral	Types I and II	CS	24	76	100	NM	NM	45	45	DNE instrument	9

AA: Addis Ababa; SNNPR: South Nation Nationalities and People Representative; NM: not mentioned; CS: cross-sectional; SD: study design; RDS: retrospective descriptive study; CO: cohort; NOS: Newcastle-Ottawa Scale; NSS: neuropathy symptom. The score: DNS: diabetic neuropathy symptom; DNE: diabetic neuropathy examination; MNSI: Michigan Neuropathy Screening Instrument.